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Biomedical Engineering |
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BME 306 Biomedical Engineering Thermodynamics Credits: (3-0) 3
Principles and applications of the three laws of thermodynamics with an emphasis on the fundamental equations of state for open and closed systems, reaction equilibrium constants, chemical potential, standard and reference state and solution thermodynamics. Apply fundamental thermodynamics principles to set up and solve problems in physiological systems.
Prerequisites: MATH 225 and BME 304
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BME 307/307L Experimental Design/Lab Credits: (2-1) 3
Students will learn engineering skills in a hands-on, project-based format. The technical learning objectives of the course include introducing students to collection, analysis and interpretation of data; and the formation of meaningful conclusions from experimental results. Additionally, students learn teamwork skills and oral and written communications by working in teams throughout the semester, preparing frequent technical progress reports, and delivering oral presentations based on the project.
Prerequisites: CSC 170/170L
Corequisites: BME 307L
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BME 308 Biomedical Engineering for Global Health Credits: (3-0) 3
This course will ask the question of how biomedical engineering can improve global health. This course will broaden understanding of global health concerns and how biomedical engineering can play a role in improving human health in developed and developing regions. This course will highlight innovative technologies and health-knowledge gaps to show how biomedical engineering can tackle some of the world’s most pressing challenges.
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BME 335/335L Biomedical Technologies/Lab Credits: (3-1) 4
Disease models (animal and organoid) and host of cell and molecular biology techniques are routinely used in biomedical research. In this course students will learn how to develop protocols for working with animals as well at PCR, ELISA that comply with Good Laboratory Practices.
Prerequisites: BIOL 151 and CHEM 114
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BME 401 Biomaterials Credits: (3-0) 3
This course will provide students with an overview of the field of biomaterials with the knowledge necessary to conduct biomedical product development and/or biomaterials research and development. Students will develop an understanding of the major classes of materials used in medical devices including metals, polymers, ceramics, composites, and natural materials. Topics covered will include material properties, material processing, testing, corrosion, biocompatibility, tissue response, and sterilization methods. Specific biomaterial applications such as dental, orthopedic, cardiovascular, drug delivery, and tissue engineering will be reviewed.
Prerequisites: MET 232
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BME 402/402L Computational Biomedical Engineering/Lab Credits: (3-1) 4
This course is intended for students interested in the crossroads of biology and computational science. The course provides the resources to use methods and software to solve computational problems.
Prerequisites: CSC 170/170L , MATH 125 , and Junior standing.
Corequisites: BME 402L
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BME 403 Cell Biomechanics Credits: (3-0) 3
This course provides the fundamental principles and concepts of biomechanical forces that develop in the human body and how they influence cell functions in a range of biological processes. Discussions will include viscoelastic theories, applications, and methods for studying biomechanics at the cellular and molecular levels.
Prerequisites: BME 303 and MATH 321
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BME 404/404L Biomedical Signal and Imaging/Lab Credits: (3-1) 4
Introduction to the application of signal and image processing methodologies and tools in the field of biomedical engineering. This course includes a hands-on laboratory component, and the students will have opportunity to operate state of the art biomedical imaging systems, such as inverted phase contrast microscopy and confocal laser scanning microscopy.
Prerequisites: CSC 170/170L , MATH 225 , and Junior standing.
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BME 405/405L Cell and Tissue Engineering/Lab Credits: (3-1) 4
This course will introduce students to the basic concept of Cell and Tissue Engineering. Cellular engineering focuses on cell based therapies, while tissue engineering and regenerative medicine seek to repair tissue damages by engineering strategies. Concepts will include applied cell and tissue engineering in stem cell and cell therapy, gene therapy, biomaterials, and drug delivery.
Prerequisites: BME 335/335L and Junior standing.
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BME 408/508 Biomedical Engineering Credits: (3-0) 3
This course provides basic concepts in biomedical engineering. Topics covered include materials for biomedical engineering, cellular and molecular processes for biomedical engineering, biological sensing, and experimental design.
Notes: Students enrolled in BME 508 will be held to a higher standard than those enrolled in BME 408.
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BME 463L Biomedical Engineering Laboratory Credits: (0-1) 1
This laboratory will introduce students to fundamental topics in bioinstrumentation and imaging, focused on the acquisition and monitoring of biomarkers and vital signs. Basic principles for the selection and appropriate use of instruments for solving bioengineering and medical problems such as cell culture, immunoassays, microscopy, electrocardiograms, and ultrasound, among others, are addressed.
Prerequisites: BME 335/335L
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BME 464 Biomedical Engineering Senior Design I Credits: (3-0) 3
Senior Design is the capstone course in Biomedical Engineering. Students will learn the engineering design process by applying knowledge and skills acquired in the undergraduate curriculum to devise a system, component, or process of biomedical engineering relevance to meet desired needs and specifications within constraints. Students will learn project management and technical communication skills. Students will prepare a design proposal, provide oral project updates, and prepare a final project report. Students will work in teams.
Prerequisites: Senior standing.
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BME 465 Biomedical Engineering Senior Design II Credits: (3-0) 3
A continuation of the Biomedical Engineering design sequence. Students will provide oral project updates, prepare a final technical design report, and participate in a design fair, including preparation of appropriate display material for the design fair.
Prerequisites: BME 464
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BME 528/528L Applied Finite Element Analysis/Lab Credits: (2-1) 3
Basic mathematical concepts of finite element analysis will be covered. The students will learn finite element modeling using state of the art software, including solid modeling. Modeling techniques for beams, frames, two and three- dimensional solids, and then walled structures will be covered in the course.
Corequisites: BME 528L
Notes: This course is cross listed with ME 428/428L/528/528L .
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BME 586 Immuno-Engineering Credits: 2 or 3
This course is taught in 3 parts. Part I is required and provides adequate and relevant background in components and functions of the immune system. Part II covers current topics in the field of immuno-engineering including nanotechnology, vaccine development and cancer therapy. Part III focuses on understanding of fluid transport in cells, tissues and organs, and advanced modeling applications associated with transport of agents via blood and lymph to immune system. Cross-listed with BME. As potential options for 2 credits, students may take either Parts I and II or Parts I and III.
Prerequisites: Pre-requisites for Part I and Part II, 2 cr hr enrollment: Biol 151
Pre-requisites for Part III, 1 cr hr enrollment: Biol 151, CBE 218, CBE 318 or POI
Notes: This course is cross listed with CBE CBE 486/586 .
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BME 601 Biomaterials Credits: (3-0) 3
This course will provide students with an overview of the field of biomaterials with the knowledge necessary to conduct biomedical product development and/or biomaterials research. The first portion of the course will provide an introduction to the major classes of materials used in medical devices including metals, polymers, ceramics, composites, and natural materials. Topics covered will include material properties, material processing, testing, corrosion, biocompatibility, tissue responses, etc. The second portion of the course will cover specific biomaterial applications such as dental, orthopedic, cardiovascular, drug delivery, and tissue engineering. The topics of implant cleanliness and sterilization methods will also be discussed. In addition, the topic of national and international governmental regulations and requirements will be reviewed including examples of investigative devices exemptions and 510k submissions.
Notes: This course is cross listed with MET 601 .
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BME 602 Anatomy and Physiology for Engineers Credits: (3-0) 3
This course introduces biomedical engineering students to fundamentals of human anatomy and physiology. Topics include engineering anthropometry, the skeletal system, skeletal muscle, the neuromuscular control system, the respiratory system, the circulatory system, the metabolic system, the thermoregulatory system, body rhythms, and an introduction to reengineering the human body.
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BME 603 Molecular Biology for Engineers Credits: (3-0) 3
This course is designed to provide a basic knowledge on molecular biology and bioinformatics that is directly applicable to engineering and related science fields. Up-to-date techniques in genetic engineering, biotechnology, and bioinformatics will be introduced for the understanding of biological problems using engineering concepts or engineering/mechanical problems through biological tools.
Notes: This course is cross listed with CBE 603 .
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BME 604 Sensing and Signal Processing Credits: (3-0) 3
Presentation of principles, characteristics, and applications of instrumentation systems including sensors, filters, instrumentation amplifiers, analog-to-digital and digital-to- analog conversions, and noise. This course will be useful to graduate students beginning their laboratory thesis research. It is available to students from other departments with permission of instructor.
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BME 606 Occupational Biomechanics Credits: (3-0) 3
Anatomical and physiological concepts are introduced to understand and predict human motor capabilities, with particular emphasis on the evaluation and design of manual activities in various occupations. Quantitative models are developed to explain muscle strength performance; cumulative and acute musculoskeletal injury; physical fatigue; and human motion control.
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BME 607 Biomechanics Credits: (3-0) 3
This course presents an introduction to biomechanics from a continuum mechanics perspective. It covers fundamental concepts of solid and fluid mechanics with applications to living systems. Topics in biosolid mechanics include stress, strain, constitutive relations, equilibrium, response to basic loading modes (extension, bending, and torsion), and buckling. Topics in biofluid mechanics include motion of a continuum, constitutive relations, fundamental balance relations, control volume and semi- empirical methods.
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BME 612 Biotech-Biomedical Engineering Credits: (3-0) 3
This course will be a survey of principles and techniques that biomedical engineers working in biotechnology and biomedical engineering will encounter in research or industry. It will serve to introduce the important advances in the state of the art in molecular and cell biology. Topics include fermentation, cell culture, recovery and purification, and technology responsible for the success of biotechnological applications, i.e., recombinant DNA technology or genetic engineering.
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BME 673 Applied Engineering Analysis I Credits: (3-0) 3
Advanced topics in engineering analysis. Special mathematical concepts will be applied to mechanical engineering problems. Topics will be selected from the following: Fourier series and boundary value problems applied to heat conduction and convection, Laplace transforms and complex variable analysis applied to vibrations and dynamic system analysis, series solutions of differential equations, partial differential equations, general matrix applications to a variety of large systems of equations in engineering, calculus of variation, and Ritz method for various engineering problems.
Notes: This course is cross listed with ME 673 .
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BME 675 Non-Thesis Practical Experience and Technical Communication Credits: 1 to 3
Students in the non-thesis track will learn aspects of technical communication and data presentation necessary for careers in biomedical engineering through lectures, interpretation of the primary literature, various writing assignments, and topical presentations.
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BME 690 Seminar Credits: (1-0) 1
A highly focused and topical course. The format includes student presentations and discussions of reports based on literature, practices, problems, and research. Seminars may be conducted over electronic media, such as internet, and are at the upper division or graduate levels. Enrollment is generally limited to 20 or fewer students.
NOTES: A total of 3 credits of BME 690 and/or BME 790 may count toward MS degree. A total of 6 credits of BME 690 and/or BME 790 may count toward PhD.
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BME 710 Experimental Design and Data Analysis in Biological Engineering Credits: (3-0) 3
This course is intended to introduce students to basic concepts and tools of experimental design and statistical analysis in biomedical research. We will discuss how to design and execute an experiment and how to use various statistical tools to estimate data parameters and test hypotheses. It is expected that students will be able to formulate a rational hypothesis from biological theory, design an experiment to test the hypothesis, and use an appropriate statistical analysis to examine the hypothesis and interpret the results upon completion of this course. The primary objective of this course is to help students understand the methodological and practical principles needed to undertake biological research and evaluate others’ research as published in the biomedical literature.
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BME 719 Nanomaterials for Biosensors Credits: (3-0) 3
Topics covered will include the fundamental principles of signal recognitions in protein, DNA, and enzyme biosensors, basic properties of nanomaterials related to sensors, electrochemical biosensors, optical and fluorescence sensors, chemiresistors, sensors based on semiconductor electronic devices, and the recent development of innovative nanomaterials for next-generation biosensors.
Prerequisites: Enrollment in one of the Biomedical Engineering, or Nanoscience & Nanoengineering, or Materials Engineering and Science programs, or Permission of Instructor.
Notes: BME 719 is cross-listed with NANO 719 and MES 719 .
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BME 724 Biopolymers Credits: (3-0) 3
This course is to survey the structure, function, properties and use of biopolymers. The course has three fifty minute lectures per week on Monday, Wednesday and Friday. Supporting reading materials will be assigned from the textbook and supplementary reading materials. Please note that the textbook is meant to supplement the lectures, not to substitute for them; you will ONLY be responsible for the materials presented in the lectures.
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BME 725 Biocomposites Credits: (3-0) 3
This course focuses on composite materials applied to bioengineering. First part of the course introduces biocomposites for medical applications and biocompatibility. Second part focuses on mechanical design and manufacturing aspects of various fibrous polymer matrix composites in terms of: i) material selection, fabrication, and characterization, ii) mechanics of composite materials, iii) design with composite materials. Third part deals with ceramic or nano composites and their applications in biomedical engineering. Final part introduces various case studies such as dental, orthopedics, prosthetic socket, and external fixator applications.
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BME 726 Biocomposites Bio/Mems and Nano Systems Credits: (3-0) 3
Application of microelectromechanical systems (MEMS) and nano-systems to biological systems, interaction of living cells and tissues with MEMS substrates and nano-engineered materials, microfluidics, engineering of inputs and outputs.
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BME 730 Vascular Mechanics and Pathology Credits: (3-0) 3
The course focuses on the artery and arterial diseases, including the genesis of heart disease. Since the artery serves as both conduit of blood flow and container of blood pressure, the course covers both the general principles and the occurrence of stress concentration in the pressure vessel. The topics included are atherosclerosis, structure and mechanics of the artery, pressure vessel principles, stress concentration in the artery, endothelial cells and low density lipoproteins, smooth muscle cells and stretch, stress reduction and atherosclerosis reduction, vein graft, intracranial aneurysms, and aortic aneurysms.
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BME 731 Advanced Biomechanics Credits: (3-0) 3
The course presents the fundamentals of continuum mechanics and nonlinear theory of elasticity with applications to the mechanical behavior of soft biological tissues.
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BME 732 Medical Imaging Credits: (3-0) 3
This course covers the physics of the major modalities commonly used in medical imaging. Also covered are the various principles and methods of constructing an image from the physical interactions of energy with living tissues, and the influence of image quality of the different modalities. Medical imaging systems to be analyzed include conventional X-ray, computed tomography (CT), magnetic resonance imaging (MRI), nuclear medicine (PET and SPECT), and ultrasound. Each of these modalities will be introduced from basic physical principles to the process of image formation. The primary focus is on the physical principles, instrumentation methods, and imaging algorithms; however, the medical interpretation of images, and clinical, research and ethical issues are also included where possible to give students a deeper understanding of the medical imaging field.
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BME 733 Cardiovascular Fluid Dynamics Credits: (3-0) 3
Mechanics of blood circulation, fluid mechanics of the heart, blood flow in arteries, unsteady flow in veins, current concepts in circulatory assist devices, biofluidics, and other selected topics. Review of cardiovascular physiology; introduction to fluid mechanics; Models of blood flow and arterial wall dynamics; Fluid mechanics and arterial disease; heart valve fluid dynamics; Ventricular assist devices.
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BME 734 Transport Phenomena in Biomedical Engineering Credits: (3-0) 3
The study of transport phenomena in biomedical systems including analysis of engineering and physiological systems and incorporation of these principles into the design of such systems. The objective of this course is for students to learn to think about, understand and model the dynamic behavior of complex biological systems. The scope of the systems to be studied is restricted to an analysis of biotransport phenomena in the human body.
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BME 735 CAD/CAM in Medicine and Surgery Credits: (3-0) 3
Introduction to computer aided design and modeling of prosthetic devices, and their subsequent manufacture using computer aided manufacturing techniques. Applications in orthopedic implant design and fabrication, dental implant design and fabrication, as well as other types of prosthetics. An advanced level review of current computer modeling and manufacturing technology for medical applications.
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BME 736 Advanced Finite Element Methods Credits: (3-0) 3
Variational and weighted residual approach to finite element equations. Emphasis on two- and three-dimensional problems in solid mechanics. Isoparametric element formulation, higher order elements, numerical integration, imposition of constraints, convergence, and other more advanced topics. Introduction to geometric and material nonlinearities. Introduction to the solution of dynamic problems and time integration. Use of finite element computer programs.
Notes: This course is cross listed with ME 736
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BME 737 Advanced Signal Processing and Imaging Credits: (3-0) 3
This course develops the theory essential to understanding the algorithms that are increasingly found in modern signal processing applications, such as speech, image processing, digital radio and audio, statistical and adaptive systems. Topics include: analysis of non-stationary signals, transform techniques, Wiener filters, Kalman filters, multirate systems and filter banks, hardware implementation and simulation of filters, and applications of multirate signal processing. Matlab will be used extensively.
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BME 738 Information Technology in Medicine Credits: (3-0) 3
Software techniques used in medical treatment and diagnosis, including transform techniques. Medical reference software engineering. Data mining. Hardware and connectivity issues. Bioinformatics.
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BME 740 Biomaterials Surface Science and Engineering Credits: (3-0) 3
This course focuses on the surface properties of biomaterials and their influence on biological and clinical outcomes. Specifically, the general surface properties of biomaterials such as surface chemistry, surface morphology, surface roughness, and surface charges will be explained. The course will cover the different instrumentation that is currently available to characterize biomaterial surfaces. Also, a variety of surface modification technologies available to engineer biomaterial surfaces will be covered as well. Example cases will be provided regularly to emphasize the biological and clinical significance of biomaterial surfaces.
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BME 742 Applied Electrochemistry Credits: (3-0) 3
This course will work from a knowledge of thermochemistry, physical chemistry, and analytical chemistry to understand the fundamental aspects of electrochemical processes in materials processing. This will include the thermodynamics and kinetics of aqueous electrochemical reactions and electrochemical measurement techniques. The course will focus on the application of electrometallurgical principles to a wide variety of industrial processes and will enable students to calculate relevant processing parameters and develop a sound understanding of electrochemical processes in materials processing.
Pre or Corequisites: Graduate standing.
Notes: This course is cross-listed with MES 742 and CBE 742 .
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BME 745 Molecular Machines Credits: (3-0) 3
This course studies forces that determine molecular structure, transport, and diffusion, macromolecular assemblies, protein synthesis, structural biology, molecular genetics, enzymology.
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BME 746 Biomimetics Credits: (3-0) 3
This course will survey recent research at the intersection of biology and mechanical/structural engineering, in particular, applications where nature’s design philosophies are applied in human-engineered structures. Multi-functional materials, hierarchical design, adaptive materials within closed loop systems, self- healing of natural structures, with a view to self-healing human engineered structures. Applications in aerospace and rehabilitation engineering.
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BME 751 Drug Delivery Credits: (3-0) 3
This course focuses on the engineering and biomolecular principles of drug therapy. Students will be introduced to the fundamentals of drug delivery, materials used for drug delivery, and controlled/targeted drug delivery strategies.
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BME 761 Bioadhesives Credits: (3-0) 3
This course will provide a survey of natural and synthetic biological adhesives that are of importance in biomedicine. Main topics include fundamentals of bioadhesion, methods of evaluating bioadhesive interactions, and concepts and strategies in designing bioadhesive systems for biomedical applications.
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BME 773 Applied Engineering Analysis II Credits: (3-0) 3
Applications of numerical methods to mechanical engineering problems. Topics will include data processing techniques, curve fitting and interpolation of experimental information, solutions to systems of ordinary differential equations, solutions to partial differential equations, and numerical integration both of known functions and functions described only by experimental data.
Notes: This course is cross listed with ME 773 .
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BME 788 Master’s Research Problems/Project Credits: 1 to 12
Independent research problems/projects that lead to research or design paper, but not to a thesis. The plan of study is negotiated by the faculty member and the candidate. Contact between the two may be extensive and intensive. Does not include research courses which are theoretical.
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BME 790 Seminar Credits: (1-0) 1
A highly focused and topical course. The format includes student presentations and discussions of reports based on literature, practices, problems, and research. Seminars may be conducted over electronic media such as internet and are at the upper division or graduate levels.
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BME 791 Independent Study Credits: 1 to 3
Includes directed study, problems, readings, directed readings, special problems, and special projects. Students complete individualized plans of study which include significant one-on-one student-teacher involvement. The faculty member and students negotiate the details of the study plans. Meetings depending upon the requirements of the topic.
Prerequisites: Permission of Instructor
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BME 792 Topics Credits: 1 to 4
Includes current topics, advanced topics and special topics. A course devoted to a particular issue in a specified field. Course content is not wholly included in the regular curriculum. Guest artists or experts may serve as instructors.
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BME 798 Thesis Credits: Credits to be arranged
A formal treatise presenting the results of study submitted in partial fulfillment of the requirements for the applicable degree. The process requires extensive and intensive one-on- one interaction between the candidate and professor with more limited interaction between and among the candidate and other members of the committee.
Notes: Credit to be arranged. Open only to students pursuing the M.S. thesis option.
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BME 888 Doctorial Research in Problems and Projects Credits: 1 to 12
Independent research problems/projects that lead to research or design paper, but not to a thesis. The plan of study is negotiated by the faculty member and the candidate. Contact between the two may be extensive and intensive. Does not include research courses which are theoretical.
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BME 896 Field Experience Credits: (0-1) 1
Students will spend a minimum of three hours per week in a hospital or another program-approved health care facility. They will observe and/or work with the technical and clinical staff in order to develop insights into the health care profession and the role of engineering in medicine as it applies to their focus area of study and research.
Notes: Required of doctoral students only.
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BME 898D Dissertation Credits: Credit to be arranged
A formal treatise presenting the results of study submitted in partial fulfillment of the requirements for the applicable degree. The process requires extensive and intensive one-on- one interaction between the candidate and professor with more limited interaction between and among the candidate and other members of the committee.
Notes: Credit to be arranged; Open only to doctoral candidates.
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Chemical and Biological Engineering |
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CBE 111/111L Introduction to Chemical Process Modeling/Lab Credits: (1-1) 2
The primary objectives of this course are: introduction to mathematical modeling of physical and chemical systems; verification of mathematical models by experiment; introduction to engineering software like Excel; development and interpretation of engineering drawings, process flow diagrams (PFD’s), and piping and instrumentation diagrams (P&ID’s); use of a drawing program, such as Visiotec; and introduction to the process simulator AspenPlus; oral and written communication of technical content to technical and non-technical audiences; and a focus on professional and academic paths in chemical engineering and related fields.
Pre or Corequisites: CHEM 112
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CBE 117L Programming for Chemical and Biological Engineering Credits: (0-1) 1
An introduction to chemical engineering through the development of computational and laboratory skills. The extended use of spreadsheets, programming, and computational software packages will be covered. Elementary numerical methods will be utilized in process modeling and laboratory experiments. Students will participate in hands-on programming exercises in a computer laboratory, or in a lab, using a tablet-pc.
Pre or Corequisites: MATH 123
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CBE 200 Undergraduate Research Credits: 1 to 3
Directed research or study of a selected problem culminating in an acceptable written report.
Prerequisites: Permission of instructor and freshman or sophomore standing.
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CBE 217 Chemical Engineering Material Balances Credits: (3-0) 3
The first course on the theory and practice of chemical engineering with emphasis on material and energy balances.
Pre or Corequisites: CHEM 114 and MATH 123 or permission of instructor.
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CBE 218 Chemical Engineering Fluid Mechanics Credits: (3-0) 3
The second course on the theory and practice of chemical engineering with emphasis on momentum transfer.
Prerequisites: MATH 125 and PHYS 211/211A , or permission of instructor.
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CBE 222 Chemical Engineering Process Thermodynamics Credits: (3-0) 3
A study of the principles and applications of thermodynamics with emphasis on the first law, the energy balance.
Prerequisites: CHEM 114 and MATH 125 , or permission of instructor.
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CBE 250 Computer Applications in Chemical Engineering Credits: (2-0) 2
The application of digital computer techniques to the solution of chemical engineering problems.
Pre or Corequisites: MATH 321 , CBE 117L or equivalent.
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CBE 317 Chemical Engineering Heat Transfer Credits: (3-0) 3
The third course on the theory and practice of chemical engineering with emphasis on heat transfer. Heat transfer by conduction, convection, and radiation is studied.
Prerequisites: CBE 217 , CBE 218 or EM 331 or ME 331 , CBE 250 or CEE 284 , and MATH 321
Pre or Corequisites: CBE 250
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CBE 318 Chemical Engineering Mass Transfer Credits: (3-0) 3
The fourth course on the theory and practice of chemical engineering with emphasis on molecular diffusion, membranes, convective mass transfer, drying, humidification, and continuous gas-liquid separation processes.
Prerequisites: CBE 218 or permission of instructor.
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CBE 321 Chemical Engineering Equilibrium Thermodynamics Credits: (3-0) 3
A continuation of CBE 222 with emphasis on the second and third laws of thermodynamics. Emphasis on thermodynamic properties of fluids, flow processes, phase and chemical equilibria.
Prerequisites: CBE 217 , CBE 222 , and MATH 225 , or permission of instructor
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CBE 333 Process Measurements and Control Credits: (1-0) 1
A study of the equipment and techniques used in monitoring process measurements and the design of feedback control systems.
Prerequisites: CBE 217 or CBE 218 or CBE 222 or permission of instructor.
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CBE 333L Chemical Engineering Process Control Lab Credits: (0-1) 1
Laboratory experiments in process measurements, feedback control loops, and industrial data acquisition and control.
Pre or Corequisites: CBE 333
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CBE 343 Chemical Kinetics and Reactor Design Credits: (3-0) 3
A study of chemical kinetics and reactor design, including techniques for analyzing kinetic data, choosing reactor operating parameters, economic optimization of homogeneous reactions, and reactor modeling.
Pre or Corequisites: CBE 317 and CBE 321 , or permission of instructor
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CBE 361L Chemical Engineering Fluid Laboratory Credits: (0-1) 1
Laboratory experiments in fluid flow, fluid flow measurements, and design of fluid handling systems.
Prerequisites: CBE 218
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CBE 362L Chemical Engineering Heat Transfer Laboratory Credits: (0-1) 1
Laboratory experiments on heat transfer.
Prerequisites: CBE 317
Corequisites: CBE 318
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CBE 364 Chemical Process Design, Economics, and Safety Credits: (2-0) 2
Chemical process design and economics topics may include time value of money, DCFROR/VPV analysis of projects and investment alternatives, after tax analysis, estimation of process operating costs, use of heuristics for equipment sizing, and estimation of process capital and equipment costs. Safety topics may include toxicology and industrial hygiene, source models, properties and prevention of fires and explosions, relief design and sizing, and hazards identification.
Prerequisites: CBE 218 and CBE 222 or permission of instructor.
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CBE 410 Brewing Science and Engineering Credits: (3-0) 3
This course will provide students with a rigorous introduction to the art of brewing by exploring the science and engineering of these processes. The course will provide background in important concepts from chemistry, microbiology, agriculture and engineering design and apply them within brewing processes such as beer and wine. Specific topics will include: raw materials (water, barley, hops, grapes), brewhouse equipment (e.g, pumps, valves, boilers, compressors, heat exchangers), engineering and plant operations (including power, cleaning, sanitation, wastewater handling and safety), fermentation, cellaring, and packaging. The course will also cover laboratory characterization methods and quality control within a regulated food/beverage production process. No alcohol will be consumed in this course.
Prerequisites: CHEM 112 and MATH 123
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CBE 410L Brewing Science and Engineering Laboratory Credits: (0-1) 1
This laboratory will provide students with a rigorous hands-on introduction to the art of brewing by exploring the science and engineering of these processes. The lab will explore important concepts from chemistry, microbiology, agriculture and engineering design and apply them within brewing processes. Brewing operations will be completed at different scales to gain an appreciation for core processing techniques as well as ancillary operations. The lab will also include analytical characterization methods for raw materials and final products along with quality control and complete analysis through waste processing. Participants must be 21 years of age or older to enroll. No alcohol will be consumed during the laboratory.
Pre or Corequisites: CBE 410
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CBE 417 Chemical Engineering Equilibrium Separations Credits: (2-0) 2
The fifth course on the theory and practice of chemical engineering with emphasis on equilibrium staged separations.
Prerequisites: CBE 321
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CBE 424/524 Molecular Modeling and Simulation Credits: (3-0) 3
Course covers topics related to computational quantum chemistry, statistical mechanics, and molecular simulation. Emphasis is placed on the use of existing methods and programs to determine thermodynamic and transport properties as well as reaction kinetic constants and mechanisms. Applications in biological systems, materials, phase equilibrium, and combustion will be discussed. Discussion of the benefits and limitations of computer simulations will accompany each course topic.
Prerequisites: CBE 321 and CHEM 114 or permission of instructor.
Notes: Students enrolled in CBE 524 will be held to a higher standard than those enrolled in CBE 424.
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CBE 433 Process Control Credits: (3-0) 3
Analysis and design of process control systems for industrial processes, including controller tuning and design of multivariable control schemes.
Prerequisites: MATH 321 and senior standing.
Notes: This course is cross listed with MET 433 .
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CBE 434/534 Design of Separation Processes Credits: (1-0) 1
Separation technology and processes are studied with application to current industrial design problems. Topics and design case studies may include: adsorption, biological separations, crystallization, distillation, environmental separations, ion exchange, membrane separations, molecular distillation, pervaporation, solid separations, supercritical extraction, thermal strippings, and others.
Prerequisites: CBE 318
Notes: Students enrolled in CBE 534 will be held to a higher standard than those enrolled in CBE 434.
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CBE 434L/534L Design of Separation Processes Laboratory Credits: (0-1) 1
Laboratory experiments in the design of separation processes, including reverse osmosis, crystallization, ultrafiltration, microfiltration, gas permeation, ion exchange, adsorption, and others.
Pre or Corequisites: CBE 434/534
Notes: Students enrolled in CBE 534L will be held to a higher standard than those enrolled in CBE 434L.
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CBE 444/544 Reactor Design Credits: (3-0) 3
Applications of chemical engineering principles to reactor design. Emphasis includes: non-isothermal reactor modeling, homogeneous and heterogeneous reactors, economics and performance optimization, catalysis, and computer simulation.
Prerequisites: CBE 343 and CBE 250
Notes: Students enrolled in CBE 544 will be held to a higher standard than those enrolled in CBE 444.
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CBE 445/545 Oxidation and Corrosion of Metals Credits: (3-0) 3
Initially, the thermodynamics of electrochemical processes are covered; use of the Nernst equation and Pourbaix diagram is presented in this material. Fundamentals of electrode kinetics are then discussed with special emphasis on the derivation of the Butler-Volmer equation and application of the Evan’s diagram. Following presentation of these fundamental concepts, phenomena observed in corrosion and oxidation such as uniform attack, pitting, stress corrosion cracking, and corrosion fatigue are discussed. Finally, selection of materials for site specific applications is covered.
Prerequisites: MET 320 or CBE 222 or ME 211 or permission of instructor.
Notes: Students enrolled in CBE 545 will be held to a higher standard than those enrolled in CBE 445. This course is cross listed with MET 445/545 .
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CBE 450/550 Systems Analysis Applied to Chemical Engineering Credits: 2 to 3
The development of mathematical models for dynamic and steady state chemical engineering systems; simulation of these complex systems using computers and software, such as AspenPlus; estimation of physical and equilibrium properties; and analysis of results.
Pre or Corequisites: CBE 417 and CBE 433 ; or permission of instructor.
Notes: Students enrolled in CBE 550 will be held to a higher standard than those enrolled in CBE 450.
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CBE 455/555 Pollution Phenomena and Process Design Credits: (3-0) 3
The study of the industrial sources of and treatment of air, water and land pollutants. The chemical and physical phenomena operating in pollution control equipment and the design of pollution control equipment will be examined. Waste minimization and pollution prevention strategies will be considered.
Prerequisites: CBE 218 , CBE 317 and CBE 318 or equivalent; or permission of instructor.
Notes: Students enrolled in CBE 555 will be held to a higher standard than those enrolled in CBE 455. This course is cross listed with CEE 555 .
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CBE 461L Chemical Engineering Mass Transfer and Reaction Engineering Laboratory Credits: (0-1) 1
Laboratory experiments on mass transfer.
Prerequisites: CBE 318 , CBE 343 and CBE 417
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CBE 463 Process Design for Chemical Engineering Credits: (2-1) 3
Economics lecture topics may include time value of money, DCFROR/NPV analysis of projects and investment alternatives, after tax analysis, and estimation of process capital, equipment, and operating costs. Process design lecture topics may include process flow diagram synthesis, process recycle structures, process conditions, process simulation and optimization, and process design heuristics. Students will work in groups on a common process design project that includes detailed equipment designs, evaluation of reactor, separations, and recycle alternatives, and economic evaluation of various process improvement ideas.
Prerequisites: CBE 317 , CBE 343 , and CBE 417 or permission of instructor
Pre or Corequisites: CBE 318 and CBE 465 ; or permission of instructor.
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CBE 465 Chemical Process Safety Credits: (2-0) 2
This course is focused on the fundamentals of safety of processes that chemical and biological engineers may be exposed. Topics may include toxicology and industrial hygiene, source models, toxic release and dispersion models, inherently safer design, fires and explosions, and their prevention, chemical reactivity, relief design and sizing, hazards identification, safety procedures and design, and study of case histories of past incidents and accidents.
Prerequisites: CBE 218 or permission of instructor.
Pre or Corequisites: CBE 317 and CBE 343
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CBE 466 Capstone Design for Chemical Engineering Credits: (0-2) 2
Students will work in design teams to complete a semester-long capstone project. The course format is predominantly design project based, featuring weekly meetings with faculty mentors. Projects will be open-ended and may vary from group to group. Projects may involve trouble shooting/optimization/redesign of an existing process. The final design package should include a comprehensive final report with PFDs, P&IDs, equipment specification sheets, and safety/economic analyses.
Prerequisites: CBE 318 and CBE 463 , or permission of instructor.
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CBE 467 Process/Product Design for CBE Credits: (2-0) 2
This course provides students with design experiences related to industries or positions that they might find themselves working. The topics may focus on design of specific processes, design of chemical/biological products (specialty products, molecular products, products with unique micro/nano structure, etc), or design and/or scale-up of unique processes and/or products.
Prerequisites: Senior standing
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CBE 474/574 Polymer Technology Credits: 2 to 3
A study of the engineering aspects of polymer synthesis and reactor design, polymer testing, polymer characterization, rheology, macro- properties, and fabrication. Students may enroll for 2 or 3credits, depending upon the particular level of course matter that matches their interest. Students taking 2 credits will take two-thirds of the course material. The instructor, in conjunction with the department head, will monitor student credit hours. Course is not repeatable for credit.
Prerequisites: Senior standing or permission of instructor.
Notes: Students enrolled in CBE 574 will be held to a higher standard than those enrolled in CBE 474.
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CBE 474L/574L Experimental Polymer Technology Credits: (0-1) 1
Laboratory experiments in polymer synthesis, chemical and mechanical property testing, extrusion, and modeling.
Pre or Corequisites: CBE 474/574
Notes: Students enrolled in CBE 574L will be held to a higher standard than those enrolled in CBE 474L.
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CBE 475/575 Advances in Processing and Nanoengineering of Polymers Credits: (2-0) 2
The course will begin with an overview of the basic principles of polymer rheology and structure formation. It will then review recent examples from the scientific literature in which concepts and theories of rheological behavior and structure formation at multiple length scales have been further developed and/or applied to the processing of polymers and composites with advanced functional and multifunctional properties. Special attention will be paid to research related to processing challenges in the formation of polymer nanocomposites, nanofibers and hierarchical composite structures. As part of this course, students will be expected to develop skills in reviewing and critically assessing the scientific literature, and in developing research strategies based on current state of knowledge.
Prerequisites: CHEM 114 and CHEM 114L or MES 604 or permission of instructor.
Notes: Students enrolled in CBE 575 will be held to a higher standard than those enrolled in CBE 475. This course is cross listed with MES 475/575 and NANO 475/575 .
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CBE 476/576 Organosilicon Polymer Chemistry and Technology Credits: (1-0) 1
An introduction to the engineering and science aspects of silicone-organic polymer chemistry from an industrial viewpoint. The course covers basic silicone nomenclature, monomer and polymerization reactions, curing, reinforcement, general applications, and hands-on laboratory exercises, which include making things like elastomeric (bouncy) putty and high-bouncing balls. The course is held during a one-week period.
Prerequisites: Senior standing or permission of instructor.
Notes: Students enrolled in CBE 576 will be held to a higher standard than those enrolled in CBE 476.
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CBE 482/582 Upstream Oil and Gas Processing Credits: 1 or 3
This course provides an overview of upstream petroleum processing technologies with relevant aspects of computer simulations to develop an understanding of complex fluid transport and fluid-phase interactions. It also covers process engineering aspects of gas and petroleum processing prior to refining. The first third of the course (1 credit) gives an overview of upstream processing and is appropriate for all students meeting the non-CBE prerequisite. The remaining 2 credit hours of the course provide a more detailed coverage of upstream petroleum process.
Prerequisites: Prerequisite for 1 credit hour part of the course: ME 331, or CBE 218, or equivalent, or permission of instructor. Prerequisite for full 3 credit hour course: CBE 321, CBE 318, and Pre/Co-requisite: CBE 417, or permission of instructor.
Notes: Students enrolled in CBE 582 will be held to a higher standard than those enrolled in CBE 482.
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CBE 483/583 Petroleum Refining Credits: 2 or 3
Overview of unit operations of Petroleum Refining. Use of heuristics to estimate performance of economics of refinery units. Application of chemical engineering principles to petroleum refining. Relevant aspects of computer‐aided process simulation for complex mixtures. The 2 lecture credit hours are for refinery overview and heuristic design-economics. The 3 lecture credit hours include Aspen modeling of ChE refinery applications.
Prerequisites: 2 credit hour prerequisites: CBE 364 or IENG 301 or IENG 302 (Engineering Economics), CBE 222 or ME 211 (Introduction to Thermodynamics), or equivalent.
3 credit hour prerequisites: CBE 343, CBE 364 and CBE 417, or permission of instructor.
Notes: Students enrolled in CBE 583 will be held to a higher standard than those enrolled in CBE 483.
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CBE 484/584 Fundamentals of Biochemical Engineering Credits: (3-0) 3
An introduction to the characterization of microorganisms, fermentation pathways, unit processes in fermentation, biochemical kinetics, and batch and continuous fermentation. The basic engineering concepts of fermentation, separation, control, and operations will be discussed.
Prerequisites: CBE 343
Corequisites: BIOL 331 or BIOL 341
Notes: Students enrolled in CBE 584 will be held to a higher standard than those enrolled in CBE 484.
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CBE 484L/584L Biochemical Engineering Laboratory Credits: (0-1) 1
Laboratory experiments in biochemical engineering. May include fermentation, dissolved oxygen mass transfer measurements, bioseparations, and other experiments to correlate with selected lecture topics.
Pre or Corequisites: CBE 484/584
Notes: Students enrolled in CBE 584L will be held to a higher standard than those enrolled in CBE 484L.
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CBE 485/585 Renewable and Sustainable Energy Credits: (3-0) 3
This course provides assessment and evaluation of current and potential energy systems; covers resources, conversion, and end-use, and emphasizes sustainable approaches meeting global energy needs in the 21st century. Different renewable and conventional energy technologies will be covered including solar, wind, geothermal, nuclear, biofuels, fossil fuels, hydrogen, fuel cells, and discussed within frameworks that aid in evaluation and analysis of energy systems engineering in the context of economics and environmental goals.
Prerequisites: Junior standing or permission of instructor.
Notes: Students enrolled in CBE 585 will be held to a higher standard than those enrolled in CBE 485.
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CBE 485L/585L Renewable and Sustainable Energy Lab Credits: (0-1) 1
This laboratory course provides hands-on experience with current and future energy systems, energy conversion calculations and efficiency measurements. Specific labs may include photovoltaics, photocatalysis, electrocatalysis, thermochemical water-splitting, biofuel production, fuel cells, and hybrid energy systems.
Pre or Corequisites: CBE 485/585 or permission of instructor.
Notes: Students enrolled in CBE 585L will be held to a higher standard than those enrolled in CBE 485L.
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CBE 486/586 Immuno-Engineering Credits: 2 or 3
This course is taught in 3 parts. Part I is required and provides adequate and relevant background in components and functions of the immune system. Part II covers current topics in the field of immuno-engineering including nanotechnology, vaccine development and cancer therapy. Part III focuses on understanding of fluid transport in cells, tissues and organs, and advanced modeling applications associated with transport of agents via blood and lymph to immune system. Cross-listed with BME. As potential options for 2 credits, students may take either Parts I and II or Parts I and III.
Pre-requisites for Part I and Part II, 2 cr hr enrollment: Biol 151
Pre-requisites for Part III, 1 cr hr enrollment: Biol 151, CBE 218, CBE 318 or POI
Prerequisites: BIOL 151
BIOL 151 , CBE 218 , CBE 318 or POI
Notes: This course is cross-listed with BME 586 .
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CBE 487 Global and Contemporary Issues in Chemical Engineering Credits: (1-0) 1
A study of contemporary global and societal issues in the field of chemical engineering.
Pre or Corequisites: CBE 364 or permission of instructor
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CBE 488/588 Applied Design of Experiments for the Chemical Industry Credits: (2-0) 2
An introduction to the engineering concepts of statistics and design of experiments as applied to chemical and biological engineering problems. Includes setup and experiments for product development or for process trials. Includes critical analysis of results of an experimental design project. The course is held during a time period that will accommodate class members and industrial speakers.
Prerequisites: Senior standing or permission of instructor.
Notes: Students enrolled in CBE 588 will be held to a higher standard than those enrolled in CBE 488.
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CBE 489/589 Composites Manufacturing Credits: (1-0) 1
A background in the concepts of polymers and polymerization as well as an overview of composites concepts, constituent materials, and manufacturing processes provide the groundwork in the first half of the course. A more detailed study of the Vacuum Assisted Resin Transfer molding (VARTM) processing builds upon this groundwork, including topics such as process materials and parameters, mold design and manufacture, and product design considerations. The course concludes with post-processing topics. In conjunction with the concepts lecture, students spend time in the lab constructing and using a simple mold which will illustrate some of the challenges of molding and finishing a composite product.
Notes: This course is cross listed with MET 489/589 . Students enrolled in CBE 589 will be held to a higher standard than those enrolled in CBE 489.
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